Blood biomarkers of vitamin D status
Blood biomarkers of vitamin D status. Zerwekh JE Am J Clin Nutr. 2008 Apr;87(4):1087S-91S. In the past quarter century, more than 50 metabolites of vitamin D have been described. To date, only a…
Biyokimya
C-reactive protein: a critical update
C-reactive protein: a critical update Mark B. Pepys and Gideon M. Hirschfield J Clin Invest. 2003;111(12):1805–1812 CRP, named for its capacity to precipitate the somatic C-polysaccharide of Streptococcus pneumoniae, was the first acute-phase…
Subclinical Hypothyroidism
Subclinical Hypothyroidism Melissa Gillett JAMA 2004;291: 228-38 Definition of Subclinical Hypothyroidism Patients with subclinical thyroid disease have few or no symptoms or signs of thyroid dysfunction and thus by its very nature subclinical…
The Limitations of Sweat Electrolyte Reference Intervals for the Diagnosis of Cystic Fibrosis: A Systematic Review
The Limitations of Sweat Electrolyte Reference Intervals for the Diagnosis of Cystic Fibrosis: A Systematic Review Avantika Mishra, Ronda Greaves, John Massie Clin Biochem Rev 2007; 28(ii):60-76 The sweat test has been used…
Ultraviolet/Visible Light Absorption Spectrophotometry in Clinical Chemistry
Ultraviolet/Visible Light Absorption Spectrophotometry in Clinical Chemistry Stephen L. Upstone in Encyclopedia of Analytical Chemistry R.A. Meyers (Ed.) pp. 1699–1714 Ultraviolet/visible (UV/VIS) absorption spectroscopy has been used in the clinical laboratory for many…
The Practice of Clinical Chemistry in the European Union
The Practice of Clinical Chemistry in the European Union Sanders et al. Clin Chem Lab Med 2002; 40(2):196–204 The European Communities Confederation of Clinical Chemistry has been actively engaged in raising the level…
The Regulation of Thyroid Function in Pregnancy
The Regulation of Thyroid Function in Pregnancy: Pathways of Endocrine Adaptation from Physiology to Pathology DANIEL GLINOER Endocrine Reviews 1997 Vol. 18, No. 3 404-432 I. Introduction II. The Regulation of Thyroid Function…
Adiponectin: A Key Adipokine in Alcoholic Fatty Liver
Adiponectin: A Key Adipokine in Alcoholic Fatty Liver Min You and Christopher Q. Rogers Exp. Biol. Med. 2009;234:850-859 Alcoholic fatty liver is a major risk factor for advanced liver injuries such as steatohepatitis,…
Mitochondrial Nitric Oxide Synthase: A Masterpiece of Metabolic Adaptation, Cell Growth, Transformation, and Death
Mitochondrial Nitric Oxide Synthase: A Masterpiece of Metabolic Adaptation, Cell Growth, Transformation, and Death Paola V. Finocchietto et al Exp. Biol. Med. 234(9): 1020—1028 Mitochondria are specialized organelles that control energy metabolism and…
Is there more to aging than mitochondrial DNA and reactive oxygen species?
Is there more to aging than mitochondrial DNA and reactive oxygen species? Mikhail F. Alexeyev FEBS Journal 276 (2009) 5768–5787 With the aging of the population, we are seeing a global increase in…
Traceability in Laboratory Medicine
Traceability in Laboratory Medicine Hubert W. Vesper and Linda M. Thienpont Clinical Chemistry. 2009;55:1067-1075 Background: In patient and population samples, generation of analytical results that are comparable and independent of the measurement system,…
Unbound (Free) Bilirubin: Improving the Paradigm for Evaluating Neonatal Jaundice
Unbound (Free) Bilirubin: Improving the Paradigm for Evaluating Neonatal Jaundice Charles E. Ahlfors, Richard P. Wennberg, J. Donald Ostrow and Claudio Tiribelli Clinical Chemistry. 2009;55:1288-1299 Background: The serum or plasma total bilirubin concentration…