The Genetic Basis of Type 2 Diabetes Mellitus: Impaired Insulin Secretion versus Impaired Insulin Sensitivity John E. Gerich Endocr. Rev. Aug 01, 1998; 19: 491-503 I. Introduction A. General considerations B. Diabetogenic vs….
Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes Joseph L. Evans, Ira D. Goldfine, Betty A. Maddux and Gerold M. Grodsky Endocrine Reviews 2002; 23 (5): 599-622 In…
Adiponectin and Adiponectin Receptors Takashi Kadowaki and Toshimasa Yamauchi Endocrine Reviews 2005; 26 (3): 439-451 Metabolic syndrome is thought to result from obesity and obesity-linked insulin resistance. Obesity in adulthood is characterized by…
Mikroalbuminüri ve Klinik Önemi Ahmet KURAL, A.Mithat BOZDAYI, Nalan KANTAROÐLU T Klin Tıp Bilimleri 1993, 13 Glomeruler hasarın ne yolla proteinüriye sebep olduğunu anlamak için, ileri derecede özelleşmiş bu kapillerlerin filtrasyon karakteristiklerini gözden…
Diabetic Nephropathy: Diagnosis, Prevention, and Treatment Jorge L. Gross, Mirela J. de Azevedo, Sandra P. Silveiro, Luís Henrique Canani, Maria Luiza Caramori, Themis Zelmanovitz, Diabetes Care 28:164-176, 2005 Diabetic nephropathy is the leading…
Low-carbohydrate nutrition and metabolism Eric C Westman, Richard D Feinman, John C Mavropoulos, Mary C Vernon, Jeff S Volek, James A Wortman, William S Yancy and Stephen D Phinney American Journal of Clinical…
Fructose, weight gain, and the insulin resistance syndrome Sharon S Elliott, Nancy L Keim, Judith S Stern, Karen Teff and Peter J Havel Am J Clin Nutr 2002;76:911–22. This review explores whether fructose…
Amino acids play central roles both as building blocks of proteins and as intermediates in metabolism. The 20 amino acids that are found within proteins convey a vast array of chemical versatility. Tertiary…
THE ROLE OF GENETIC POLYMORPHISMS IN ALCOHOLIC LIVER DISEASE FELIX STICKEL and CHRISTOPH H. ÖSTERREICHER Alcohol and Alcoholism 2006 41(3):209-224 “Chronic alcohol consumption is a major cause of liver cirrhosis which, however, develops…
Apoptozis ders notu Engin ULUKAYA Tam metin için tıklayınız “Apoptozis klasik hücre ölüm şekli olarak bilinen nekrozisden birçok özelliği açısından oldukça farklı olan bir hücre ölüm mekanizmasıdır. Biyolojik bilimler literatüründe apoptozis terimi, ilk…
Diyabetik Nefropati Patogenezi ve Tedavisi Ahmet ÇORAKÇI T Klin J Endocrin 2003, 1 “DN’de temel patolojik bozukluk glomerul’dedir. Bazal membran kalınlasması ile mezangial büyümeye bağlı olarak glomerulde genisleme ortaya çıkar. Tüm böbrek hacim…
BIRIM CEVIRME AFP Amonyak Bakır Bilirubin BUN Demir Fibrinojen Flor Folat Fosfor Galaktoz Glukoz Glutatyon Hemoglobin HDL İnsülin İyot Kalsiyum Kolesterol Kortizol Kreatinin Laktat LH Pirüvat Protoporfirin T4 Testosteron Trigliserid Üre Ürik Asit…