Experimental model of induction of diabetes mellitus in rats

Experimental model of induction of diabetes mellitus in rats
Eliziane Nitz de Carvalho; Nestor Antônio Schmidt de Carvalho; Lydia Masako Ferreira

Acta Cir. Bras. vol.18 no.spe São Paulo 2003

Diabetes mellitus is a potentially morbid condition with high prevalence worldwide, thus being a major medical concern. Experimental models play an important role in understanding such a disease, which is treatable only. This study describes a rat diabetes mellitus model induced by administering a reduced dose of alloxan, thus greatly reducing the animals death rate.